MANNITOL 25% SDV 25X50 ML
Details
Details
MANNITOL 25% SDV 25X50 ML
DESCRIPTION
Mannitol is a 6-carbon sugar alcohol and has the following structure:
C6H14O6 182.17
Mannitol occurs naturally in fruits and vegetables, and is metabolically inert in humans.
Mannitol Injection, USP, 25%, an osmotic diuretic, is a sterile, nonpyrogenic solution of mannitol in Water for Injection. It is a supersaturated solution at room temperature.
Each mL contains: Mannitol 250 mg; Water for Injection q.s. The osmolar concentration is 1372 mOsmol/L (calc.). It contains no antimicrobial agents. The pH of a 5% solution is between 4.5 and 7.0.
INDICATIONS AND USAGE
For Intravenous Injection
Mannitol Injection, USP is indicated for the following therapeutic uses:
• The promotion of diuresis, in the prevention and/or treatment of the oliguric phase of acute renal failure before irreversible renal failure becomes established.
• The reduction of intracranial pressure and treatment of cerebral edema by reducing brain mass.
• The reduction of elevated intraocular pressure when it cannot be lowered by other means.
• The promotion of urinary excretion of toxic substances.
For Urologic Irrigation
Mannitol solution, 2.5% is indicated as an irrigation solution in transurethral prostatic resection or other transurethral surgical procedures.