INSULIN HUMULIN 70/30 U/ML MDV 10 ML

**REFRIGERATED PRODUCT**

INSULIN HUMULIN 70/30 U/ML MDV 10 ML

RX - PHARMACEUTICAL

DESCRIPTION

Insulin human is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. The amino acid sequence of insulin in humans is identical to human insulin and has the empirical formula C257H383N65O77S6 with a molecular weight of 5.808 kDa.

HUMULIN 70/30 (insulin isophane human and insulin human) injectable suspension is a mixture of 70% insulin isophane human suspension, an intermediate-acting insulin, and 30% insulin human injection, a short-acting insulin. HUMULIN 70/30 is a suspension of crystals produced from combining insulin human and protamine sulfate under appropriate conditions for crystal formation and mixing with insulin human injection.

HUMULIN 70/30 is a sterile, white, and cloudy suspension that contains insulin isophane human suspension (NPH) and insulin human injection (regular) for subcutaneous use. Each milliliter of HUMULIN 70/30 contains 100 units of insulin human, dibasic sodium phosphate (3.78 mg), glycerin (16 mg), meta cresol (1.6 mg), phenol (0.65 mg), protamine sulfate (0.24 mg), zinc oxide content adjusted to provide 0.025 mg zinc ion, and Water for Injection. The pH is 7.0 to 7.8. Sodium hydroxide and/or hydrochloric acid may be added during manufacture to adjust the pH.

INDICATION AND USAGE

HUMULIN 70/30 is a fixed ratio insulin formulation indicated to improve glycemic control in adults with diabetes mellitus.

Storage and Handling

Dispense in the original sealed carton with the enclosed Instructions for Use.

Protect from heat and light. Do not freeze. Do not use it if it has been frozen.

When stored at room temperature, HUMULIN 70/30 vials can only be used for a total of 31 days including both not-in-use (unopened) and in-use (opened) storage time.