EPINEPHRINE 30MG MDV 30 ML

EPINEPHRINE 30MG MDV 30 ML
 

DESCRIPTION

Epinephrine Injection, USP is a clear, colorless, sterile solution containing 1 mg/mL epinephrine, packaged as 30 mL of solution in a multiple dose amber glass vial. In the 30 mL vial, each 1 mL of Epinephrine Injection, USP solution contains 1 mg epinephrine, 9 mg sodium chloride, 1.5 mg sodium metabisulfite, hydrochloric acid to adjust pH, 5.4 mg chlorobutanol as a preservative and water for injection. The pH range is 2.2-5.0.
 

Epinephrine is a sympathomimetic catecholamine. The chemical name of epinephrine is: 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, or (-)-3,4-Dihydroxy-α-[2-(methylamino)ethyl]benzyl alcohol.
The chemical structure of epinephrine is:

The molecular weight of epinephrine is 183.2.
 

Epinephrine solution deteriorates rapidly on exposure to air or light, turning pink from oxidation to adrenochrome and brown from the formation of melanin.

INDICATIONS AND USAGE

1.1 Anaphylaxis

Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from insect stings or bites, foods, drugs, sera, diagnostic testing substances, and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.

 

1.2 Hypotension associated with Septic Shock

Epinephrine Injection, USP is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.